Comparison of the PED alone and PED combined with coiling groups before propensity score matching in the 967 aneurysms with angiographic follow-up
| Variable | PED alone | PED combining coils | P value |
| No. of aneurysms (%) | 496 | 471 | |
| Age (years) | 14–82 | 3–78 | |
| Mean (SD) | 53.06 (±11.11) | 54.30 (±11.36) | 0.084 |
| Female | 330 (66.5) | 368 (78.1) | <0.001 |
| Comorbidities | |||
| Hypertension | 150 (30.2) | 168 (35.7) | 0.073 |
| Diabetes | 19 (3.8) | 27 (5.7) | 0.165 |
| Hyperlipidaemia | 21 (4.2) | 14 (3.0) | 0.305 |
| Coronary heart disease | 28 (5.6） | 22 (4.7） | 0.494 |
| Alcohol abuse | 68 (13.7） | 46 (9.8） | 0.057 |
| Smoking | 140 (28.2） | 102 (21.7） | 0.018 |
| Aneurysm presentation | 0.006 | ||
| Incidental | 262 (52.8) | 202 (42.9) | 0.002 |
| Symptomatic | 217 (43.8) | 254 (53.9) | 0.002 |
| Ruptured (history of SAH) | 17 (3.4) | 15 (3.2) | 0.833 |
| Pretreatment mRS | 0.807 | ||
| ≤2 | 455 (91.7) | 430 (91.3) | |
| >2 | 41 (8.3) | 41 (8.7) | |
| Multiple aneurysms | 159 (32.1) | 133 (28.2) | 0.196 |
| Ruptured aneurysms | 17 (3.4) | 15 (3.2) | 0.833 |
| Morphology | <0.001 | ||
| Saccular | 379 (76.4) | 430 (91.8) | <0.001 |
| Fusiform | 58 (11.7) | 24 (4.8) | 0.001 |
| Dissecting | 47 (9.5) | 11 (2.2) | <0.001 |
| Blister | 12 (2.4) | 6 (1.2) | 0.188 |
| Maximal diameter in mm (mean） | 9.99 (±7.57) | 15.13 (±8.08) | <0.001 |
| ≤7 mm | 230 (46.4) | 86 (18.3) | <0.001 |
| 7–15 mm | 168 (33.9) | 197 (41.8) | 0.011 |
| >15 mm | 98 (19.7) | 188 (39.9) | <0.001 |
| Location | <0.001 | ||
| Carotid artery | 376 (75.8) | 419 (89.6) | <0.001 |
| Distal circle of Willis | 25 (5.1) | 14 (3.0) | 0.102 |
| Vertebral artery | 82 (16.5) | 24 (5.0) | <0.001 |
| Basilar artery and other posterior circulation | 13 (2.6) | 14 (3.0) | 0.740 |
| PED model | 0.116 | ||
| PED Classic | 213 (42.9%） | 226 (48.0%） | |
| PED Flex | 283 (57.1) | 245 (52.0) | |
| Time to last follow-up imaging (mean) | 9.05 (±6.53) | 9.01 (±7.59) | 0.574 |
| Complete occlusion at last follow-up | 382 (77.0) | 407 (86.4) | <0.001 |
| mRS score at last follow-up | 0.554 | ||
| ≤2 | 458 (92.3) | 430 (91.3) | |
| >2 | 38 (7.7) | 41 (8.7) | |
| Complications | |||
| Ischaemic complications | 27 (5.4) | 58 (12.1) | <0.001 |
| Haemorrhagic complications | 22 (4.5) | 24 (5.1) | 0.681 |
| DAR | 12 (2.4) | 11 (2.3) | 0.932 |
| DIPH | 10 (2.0) | 13 (2.8) | 0.448 |
| Compression symptoms | 20 (4.0) | 31 (6.6) | 0.076 |
| Mortality | 9 (1.8) | 9 (1.9) | 0.912 |
Bold values: p value <0.05.
n (%); p value: χ2 test.
Median (IQR); p value: t-test.
DAR, delayed aneurysm rupture; DIPH, distal intraparenchymal haemorrhage; mRS, modified Rankin scale; PED, Pipeline embolisation device; SAH, subarachnoid haemorrhage.