Table 3

Association between intracranial artery or carotid artery atherosclerotic diseases and ipsilateral ACI

Presence of ipsilateral ACI
Univariate regressionMultivariate regression*
OR95% CIP valueOR95% CIP value
Intracranial artery stenosis ≥50%3.0901.757 to 5.432<0.0013.0091.637 to 5.531<0.001
Carotid stenosis ≥50%2.7991.297 to 6.0410.0092.5611.116 to 5.8780.026
Carotid MWT ≥1 mm2.6841.716 to 4.199<0.0012.4951.521 to 4.093<0.001
Carotid calcification1.4550.939 to 2.2540.0931.4280.871 to 2.3400.158
Carotid LRNC1.5530.996 to 2.4210.0521.2730.776 to 2.0900.340
Carotid IPH1.3690.680 to 2.7560.3791.7450.802 to 3.7990.160
Carotid HRP0.9590.532 to 1.7300.8900.9860.511 to 1.9010.967
  • *Adjusted for confounding factors of age, gender, body mass index, hypertension, diastolic blood pressure, high-density lipoprotein, total cholesterol, smoking and diabetes. The regression analysis for carotid FCR (fibrous cap rupture) was not applicable due to very few cases.

  • ACI, acute cerebral infarct; HRP, high-risk plaque; IPH, intraplaque haemorrhage; LRNC, lipid-rich necrotic core; MWT, mean wall thickness.