Table 4

Predictive factors of stroke in patients with TAK during disease course

	Crude HR			Adjusted HR
	HR	95% CI	P value	HR	95% CI	P value
Age	1.02	1.00 to 1.03	0.049	1.02	1.00 to 1.04	0.043
Sex
Female	1.00 (ref)			1.00 (ref)
Male	0.78	0.41 to 1.49	0.455	0.83	0.44 to 1.58	0.573
Type of insurance
National Health Insurance	1.00 (ref)			1.00 (ref)
Medical aid	1.88	0.69 to 5.16	0.219	1.93	0.70 to 5.33	0.205
Comorbidities
Hypertension	0.96	0.60 to 1.51	0.844	0.85	0.51 to 1.42	0.527
Diabetes mellitus	1.13	0.64 to 2.00	0.666	1.13	0.62 to 2.09	0.688
Dyslipidaemia	0.88	0.55 to 1.39	0.572	0.80	0.47 to 1.36	0.408
Atrial fibrillation and flutter	1.95	0.71 to 5.34	0.196	1.66	0.59 to 4.69	0.340
Administered medication*
Immunosuppressive treatments
Glucocorticoid treatment ≥3 months	0.74	0.38 to 1.46	0.388	0.82	0.38 to 1.79	0.624
Azathioprine	0.72	0.31 to 1.70	0.458	0.86	0.35 to 2.12	0.740
Methotrexate	0.72	0.37 to 1.39	0.322	0.85	0.41 to 1.77	0.660
Antiplatelet therapy
Aspirin	0.84	0.51 to 1.37	0.483	0.78	0.45 to 1.34	0.364
Clopidogrel	1.25	0.70 to 2.21	0.454	1.40	0.75 to 2.60	0.290
Statins	0.91	0.55 to 1.51	0.718	0.83	0.46 to 1.50	0.544