Univariate analysis between unruptured and ruptured groups in the derivation and validation set
| Characteristic | Derivation cohort (n=1171) | Validation cohort (n=500) | ||||
| Unruptured N (%) | Ruptured N (%) | P value | Unruptured N (%) | Ruptured N (%) | P value | |
| No of aneurysm | 1067 (91.1) | 104 (8.9) | 446 (89.2) | 54 (10.8) | ||
| Female sex | 734 (68.8) | 79 (76.0) | 0.130 | 294 (65.9) | 40 (74.1) | 0.229 |
| Age (years) | ||||||
| <50 | 214 (20.1) | 23 (22.1) | 0.178 | 80 (17.9) | 12 (22.2) | 0.205 |
| 50–70 | 728 (68.2) | 63 (60.6) | 307 (68.8) | 31 (57.4) | ||
| ≥70 | 125 (11.7) | 18 (17.3) | 59 (13.2) | 11 (20.4) | ||
| History of SAH | 56 (5.2) | 23 (22.1) | <0.001 | 22 (4.9) | 12 (22.2) | <0.001 |
| No of aneurysms | ||||||
| 2 | 636 (59.6) | 65 (62.5) | 0.830 | 271 (60.8) | 37 (68.5) | 0.442 |
| 3–4 | 382 (35.8) | 35 (33.7) | 155 (34.8) | 16 (29.6) | ||
| >4 | 49 (4.6) | 4 (3.8) | 20 (4.4) | 1 (1.9) | ||
| Comorbidities | ||||||
| Hypertension | 562 (52.7) | 62 (59.6) | 0.175 | 234 (52.5) | 35 (64.8) | 0.086 |
| Diabetes | 128 (12.0) | 8 (7.7) | 0.191 | 42 (9.4) | 2 (3.7) | 0.207 |
| Hypercholesterolaemia | 111 (10.4) | 10 (9.6) | 0.801 | 50 (11.2) | 7 (13.0) | 0.702 |
| Heart diseases | 113 (10.6) | 5 (4.8) | 0.061 | 36 (8.1) | 6 (11.1) | 0.436 |
| History of stroke | 123 (11.5) | 8 (7.7) | 0.236 | 53 (11.9) | 7 (13.0) | 0.818 |
| Smoking | 199 (18.7) | 20 (19.2) | 0.885 | 84 (18.8) | 15 (27.8) | 0.119 |
| Drinking | 141 (13.2) | 18 (17.3) | 0.145 | 70 (15.7) | 14 (25.9) | 0.058 |
| Morphological characterises | ||||||
| Size, mm | ||||||
| <3 | 291 (27.3) | 14 (13.5) | 0.012 | 127 (28.5) | 135 (27.0) | 0.102 |
| 3–7 | 573 (53.7) | 65 (62.5) | 235 (52.7) | 34 (63.0) | ||
| 7–15 | 170 (15.9) | 23 (22.1) | 84 (18.8) | 12 (22.2) | ||
| >15 | 33 (3.1) | 2 (1.9) | ||||
| Neck >3.9 | 379 (35.5) | 41 (39.4) | 0.428 | 168 (37.7) | 21(389) | 0.861 |
| AR >1.5 | 196 (18.4) | 41 (39.4) | <0.001 | 95 (21.3) | 23 (46.2) | 0.001 |
| Branching to parent ratio >1.2 | 187 (17.5) | 33 (31.7) | <0.001 | 86 (19.3) | 17 (31.5) | 0.036 |
| Neck to parent ratio >1.2 | 325 (30.5) | 41 (39.4) | 0.060 | 138 (30.9) | 14 (25.9) | 0.449 |
| SR >1.7 | 204 (19.1) | 42 (40.4) | <0.001 | 95 (21.3) | 21 (38.9) | 0.004 |
| Location of PC | 109 (10.2) | 23 (22.1) | <0.001 | 42 (9.4) | 10 (18.5) | 0.039 |
| Irregular shape | 357 (33.5) | 53 (51.0) | <0.001 | 155 (34.8) | 35 (64.8) | <0.001 |
| Bifurcation location | 236 (22.1) | 41 (39.4) | <0.001 | 109 (24.4) | 24 (44.4) | 0.002 |
| Inflow angle, mean (SD) | 96 (35) | 103 (33) | 0.055 | 99 (31) | 104 (31) | 0.351 |
| Outflow angle, mean (SD) | 102 (31) | 102 (29) | 0.866 | 100 (30) | 106 (29) | 0.172 |
| Branching angle, mean (SD) | 137 (34) | 128 (36) | 0.021 | 137 (35) | 134 (33) | 0.045 |
AR, aspect ratio; PC, posterior circulation; SAH, subarachnoid haemorrhage; SR, size ratio.