Risk of subarachnoid haemorrhage according to the presence of diabetes mellitus
| Group | Participants (n) | Patient-years at risk | Events (n) | Estimated event rates (95% CI)* | Sex and age-adjusted model | Fully adjusted model† | ||
| Adjusted HR (95% CI) | P value | Adjusted HR (95% CI) | P value | |||||
| Non-diabetes | 381 406 | 4 435 095 | 962 | 21.69 (20.34 to 23.11) | 1 (ref) | – | 1 (ref) | – |
| Diabetes | 40 362 | 448 998 | 77 | 17.15 (13.53 to 21.43) | 0.73 (0.58 to 0.93) | 0.010 | 0.68 (0.53 to 0.86) | <0.001 |
Adjusted HR (95% CI) and p values are derived by multivariate Cox proportional hazards regression models for subarachnoid haemorrhage.
*Rate per 100 000 person-years.
†Adjusted for age, sex, systolic blood pressure, body mass index, total cholesterol, household income, lifestyle habits (exercise, smoking, alcohol), antihypertensive agents, statins, interaction between systolic blood pressure and antihypertensive agents and interaction between total cholesterol and statins.