Table 1

Laboratory parameters over the course of time in both patients

Variable (reference units)d1*d2*d3*d4*d5*d6*d7*d8*d9*d10*d18†
Patient 1
(39 years, first ChAdOx1 nCov-19 vaccination 8 days before hospital admission)
CSVT
 Platelets (140–440×109/L)84615136476710410498121126
 D-dimer (0.5 mg/L)14.211.411.811.914.49.368.637.17.654.140.91
 Fibrinogen (210–400 mg/dL)23623417314383626490201292285
 Coagulation factor 13 (>70%)119117947767686599
 CRP (<5.0 mg/L)1.32.90.7<0.6<0.6<0.6<0.6<0.66.2
 Ferritin (9–140 ng/mL)83100786863
 Interleukin 6 (0–7.0 pg/mL)1243.63.64.2
Patient 2
(24 years, first ChAdOx1 nCov-19 vaccination 12 days before hospital admission)
CSVT
 Platelets (140–440×109/L)294178135166188258304337254183
 D-dimer (0.5 mg/L)>3323.614.62.811.811.532.912.813.312.251.35
 Fibrinogen (210–400 mg/dL)9555<50<50<50<50152169208232254
 Coagulation factor 13 (>70%)253622465898
 CRP (<5.0 mg/L)16.714.29.43.72.61.71.33.93.11.31.5
 Ferritin (9–140 ng/mL)806147
 Interleukin 6 (0–7.0 pg/mL)112.72.5
  • *Hospital treatment

  • †Follow-up visit 1 week after hospital discharge

  • CRP, C reactive protein; CSVT, cerebral sinus venous thrombosis (diagnosis); d, day.