Table 1

Baseline clinical characteristics and outcomes of the study patients with intracerebral haemorrhage

VariableTotal (n=3255)With any medical complications (n=878)Without medical complications (n=2377)P value
Age, mean±SD (years)62±1366±1361±13<0.0001
Age ≥65 years, n (%)1414 (43.44)499 (56.83)915 (38.49)<0.0001
Gender, female, n (%)1260 (38.71)352 (40.09)908 (38.20)0.3254
Hypertension, n (%)2191 (67.31)593 (67.54)1598 (67.23)0.8661
Hyperlipidaemia, n (%)230 (7.07)56 (6.38)174 (7.32)0.3519
Diabetes mellitus, n (%)285 (8.76)88 (10.02)197 (8.29)0.1201
History of stroke, n (%)889 (27.31)272 (30.98)617 (25.96)0.0043
History of TIA, n (%)29 (0.89)10 (1.14)19 (0.80)0.3601
History of AF, n (%)54 (1.66)20 (2.2834 (1.43)0.0929
History of coronary heart disease (CHD), n (%)204 (6.27)65 (7.40)139 (5.85)0.1042
Family history of stroke, n (%)491 (15.08)119 (13.55)372 (15.65)0.138
Medical history, n (%)
 Antihypertension treatment1910 (58.68)566 (64.46)1344 (56.54)<0.0001
 Antiplatelet treatment31 (0.95)8 (0.91)23 (0.97)0.883
 Anticoagulant treatment24 (0.74)9 (1.03)15 (0.63)0.2435
 Hypoglycaemic treatment405 (12.44)152 (17.31)253 (10.64)<0.0001
 Lipid-lowering treatment275 (8.45)57 (6.49)218 (9.17)0.0147
Current smoking, n (%)825 (25.35)208 (23.69)617 (25.96)0.187
Current heavy drinking, n (%)998 (30.66)243 (27.68)755 (31.76)0.0248
Baseline NIHSS, median (IQR)10.0 (4.0–18.0)16 (9.0–25.0)8 (3.0–14.00)<0.0001
GCS at admission, median (IQR)14.0 (9.0–15.0)10 (6.0–15.0)15 (11–15.0)<0.0001
Haematoma volume, median (IQR)12.6 (5.5–28.0)18.64 (7.5–41.8)11.76 (4.8–24.0)<0.0001
Haematoma location, n (%)
 Basal ganglia1878 (57.7)492 (56.04)1386 (58.31)0.2442
 Lobar704 (21.63)215 (24.49)489 (20.57)0.016
 Thalamus631 (19.39)178 (20.27)453 (19.06)0.4362
 Brainstem258 (7.93)95 (10.82)163 (6.86)0.0002
 Cerebellum184 (5.65)57 (6.49)127 (5.34)0.2077
Death during hospitalisation, n (%)297 (9.12)184 (20.96)113 (4.75)<0.0001
Death at 3 months, n (%)650 (19.97)337 (38.38)313 (13.17)<0.0001
Death at 6 months, n (%)732 (22.49)361 (41.12)371 (15.61)<0.0001
Death at 12 months, n (%)850 (26.11)396 (45.10)454 (19.10)<0.0001
  • AF, atrial fibrillation; GCS, Glasgow Coma Scale; NIHSS, National Institutes of Health Stroke Scale; TIA, transient ischaemic attack.