Table 2

Main safety and functional outcomes of patients

Outcome	Group	n (%)	Unadjusted		Multivariable adjusted*		PS adjusted
Outcome	Group	n (%)	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
mRS 0–1 at 3 months	Intravenous t-PA	338 (89.4)	Ref		Ref		Ref
	Aspirin	202 (87.8)	0.85 (0.51 to 1.43)	0.55	0.83 (0.46 to 1.50)	0.53	0.80 (0.46 to 1.41)	0.44
	DAPT	188 (87.4)	0.82 (0.49 to 1.39)	0.47	0.84 (0.46 to 1.52)	0.56	0.84 (0.48 to 1.48)	0.55
mRS 0–2 at 3 months	Intravenous t-PA	359 (95.0)	Ref		Ref		Ref
	Aspirin	213 (92.6)	0.66 (0.34 to 1.30)	0.23	0.65 (0.30 to 1.39)	0.26	0.58 (0.28 to 1.22)	0.15
	DAPT	199 (92.6)	0.66 (0.33 to 1.31)	0.23	0.67 (0.31 to 1.48)	0.33	0.64 (0.31 to 1.34)	0.23
Mortality at 3 months	Intravenous t-PA	2 (0.5)	Ref		Ref		Ref
	Aspirin	2 (0.9)	1.68 (0.24 to 12.00)	0.61	0.99 (0.10 to 10.46)	0.92	1.46 (0.17 to 12.95)	0.73
	DAPT	0 (0.0)	–	0.96	–	1.00	–	0.94

*Adjusted for sex, age, smoking, hypertension, hyperlipidaemia, diabetes mellitus, atrial fibrillation, previous stroke, previous TIA, blood glucose, blood pressure, weight, NIHSS score and mRS prior to stroke.
DAPT, dual antiplatelet therapy; EMR, electronic medial record; mRS, modified Rankin scale; NIHSS, National Institutes of Health Stroke Scale; NINDS, National Institute of Neurological Disorders and Stroke rt-PA Stroke Study experience; PS, propensity score; TIA, transient ischaemic attack; t-PA, tissue plasminogen activator.