Patient, disease and treatment characteristics
| Categorical and dichotomous variables | Whole cohort | Femoral | Radial | Pearson χ2 |
| Pre-stroke independence (mRS 0–2) | 90.1% (338/375) | 88.2% (216/245) | 93.8% (122/130) | OR 2.05 (0.91–4.62) p=0.079 |
| Operator three performing procedure | 35.2% (132/375) | 6.1% (15/245) | 90 .% (117/130) | OR 138 (64–300) p=0.000 |
| Wake-up stroke/onset unknown | 31.5% (118/375) | 29.8% (73/245) | 34.6% (45/130) | OR 1.25 (0.79–1.96) p=0.339 |
| Female | 50.7% (190/375) | 51.4% (126/245) | 49.2% (64/130) | OR 0.92 (0.60–1.40) p=0.685 |
| Use of CTA | 95.7% (359/375) | 96.3% (236/245) | 94.6% (123/130) | OR 0.67 (0.24–1.84) p=0.435 |
| Use of CTP | 65.6% (246/375) | 66.1% (162/245) | 64.6% (84/130) | OR 0.94 (0.60–1.46) p=0.770 |
| Intracranial large vessel occlusion site | ||||
| Internal Carotid Artery | 24.3% (91/375) | 22.4% (55/245) | 27.7% (36/130) | |
| Middle Cerebral Artery M1 segment | 52 .% (195/375) | 51 .% (125/245) | 53.8% (70/130) | |
| Middle Cerebral Artery M2 segment | 23.5% (88/375) | 26.1% (64/245) | 18.5% (24/130) | |
| Aneterior Cerebral Artery | 0.3% (1/375) | 0.4% (1/245) | 0 .% (0/130) | P=0.290 *Cochran–Mantel |
| IV TPA prior to MT | 9.9% (37/375) | 11.8% (29/245) | 6.2% (8/130) | OR 0.49 (0.22–1.10) p=0.079 |
| GA | 89.9% (337/375) | 91.4% (224/245) | 86.9% (113/130) | OR 0.62 (0.32–1.23) p=0.169 |
| GA induction before arteriotomy | 35.9% (121/337) | 29.9% (67/224) | 47.8% (54/113) | OR 2.14 (1.34–3.42) p=0.001 |
| Aspiration only (no stent-retriever) | 34.9% (131/375) | 31.4% (77/245) | 41.5% (54/130) | OR 0.65 (0.42–1.00) p=0.051 |
| Carotid stenting | 16 .% (60/375) | 14.7% (36/245) | 18.5% (24/130) | OR 1.31 (0.75–2.32) p=0.344 |
| Intracranial stenting | 5.6% (21/375) | 4.9% (12/245) | 6.9% (9/130) | OR 1.44 (0.59–3.52) p=0.417 |
| Continuous variables—median (IQR) | Whole cohort | Femoral | Radial | Mann-Whitney U test |
| Age | 75 (64–84) | 76 (64–85) | 74 (62–83) | P=0.375 |
| NIHSS | 14 (8.5–19) | 14 (8–19) | 15 (10–19) | P=0.231 |
| RACE | 6 (3.5–8) | 6 (3–8) | 6 (5–8) | P=0.140 |
| ASPECTS | 9 (8–10) | 9 (8–10) | 9 (8–10) | P=0.053 |
| Onset/last known normal to ER presentation (mins) | 120 (65–401) | 110 (63.5–321) | 150 (65.5–602) | P=0.103 |
| ER presentation to CT (min) | 17 (12–29) | 17 (12–27) | 18 (12–34) | P=0.515 |
| CT to arteriotomy (min) | 59.5 (37–84) | 58.5 (35–85) | 60 (40–84) | P=0.777 |
| Arteriotomy to reperfusion (min) | 29 (19–46.5) | 30 (20–40) | 25 (17–43) | P=0.036 |
| CT to reperfusion (min) | 95.5 (70–126.5) | 96.5 (71–130) | 95 (68–123) | P=0.456 |
| Days in MT hospital | 4 (2–8) | 4 (2–8) | 4 (2–7) | P=0.888 |
ER, emergency room; GA, general anaesthesia; ICA, internal carotid artery; IV, intravenous; mRS, modified Rankin score; MT, mechanical thrombectomy.