Table 3

Correlations of biomarker levels with eGFR on both linear and log–log scales using Spearman rank and Pearson correlations

Biomarker	eGFR		Log eGFR		Log eGFR
Biomarker	R (unadjusted)	P value	R² (unadjusted)	P value	R² (age-adjusted)	P value
Inflammatory markers
IL-6	−0.18	<0.001	0.03	<0.001	0.002	0.18
CRP	−0.07	0.049	0.01	0.02	0.001	0.29
NGAL	−0.26	<0.001	0.06	<0.001	0.03	<0.001
sTNF-R1	−0.41	<0.001	0.21	<0.001	0.12	<0.001
Thrombotic or antiatherogenic markers
TM	−0.35	<0.001	0.13	<0.001	0.10	<0.001
Fibrinogen	−0.15	<0.001	0.02	<0.001	0.01	0.02
vWF	−0.27	<0.001	0.08	<0.001	0.02	<0.001
P-selectin	−0.08	0.008	0.003	0.05	0.001	0.33
PZ	0.03	0.298	0.001	0.48	0.001	0.35
D-dimer	−0.34	<0.001	0.11	<0.001	0.01	0.01
Anti-PC	0.05	0.125	0.002	0.21	0.003	0.13
ADAMTS-13	0.09	0.008	0.007	0.02	0.0008	0.40
Markers of cardiac or neuronal function/injury
NT-proBNP	−0.38	<0.001	0.14	<0.001	0.05	<0.001
hFABP	−0.56	<0.001	0.34	<0.001	0.20	<0.001
NSE	−0.08	0.009	0.01	0.003	0.005	0.02
BDNF	0.01	0.852	0	0.99	0.0002	0.6

Anti-PC, antiphosphorylcholin; BDNF, brain-derived neurotrophic factor; CRP, C-reactive protein; hFABP, heart-type fatty-acid-binding protein; IL-6, interleukin-6; NGAL, neutrophil-gelatinase-associated lipocalin; NSE, neuron-specific enolase; NT-proBNP, N-terminal pro-B-type natriuretic peptide; PZ, Protein Z; sTNF-R1, soluble tumour necrosis factor receptor-1; TM, thrombomodulin; vWF, von Willebrand factor.