Coexisting intracranial artery stenosis ≥50% and | Presence of ipsilateral ACI | |||||
Univariate regression | Multivariate regression* | |||||
OR | 95% CI | P value | OR | 95% CI | P value | |
Carotid stenosis ≥50% | 2.014 | 0.627 to 6.477 | 0.240 | 1.319 | 0.359 to 4.845 | 0.677 |
Carotid MWT ≥1 mm | 5.043 | 2.378 to 10.694 | <0.001 | 4.313 | 1.937 to 9.601 | <0.001 |
Carotid calcification | 3.864 | 1.723 to 8.664 | 0.001 | 3.606 | 1.513 to 8.593 | 0.004 |
Carotid LRNC | 2.803 | 1.455 to 5.401 | 0.002 | 2.358 | 1.166 to 4.769 | 0.017 |
Carotid IPH | 1.897 | 0.418 to 8.605 | 0.407 | 1.474 | 0.269 to 8.078 | 0.655 |
Carotid HRP | 1.418 | 0.403 to 4.992 | 0.586 | 1.294 | 0.311 to 5.374 | 0.723 |
*Adjusted for confounding factors of age, gender, body mass index, hypertension, diastolic blood pressure, high-density lipoprotein, total cholesterol, smoking and diabetes. The regression analysis for coexisting intracranial artery stenosis ≥50% and carotid FCR (fibrous cap rupture) was not applicable due to very few cases.
ACI, acute cerebral infarct; HRP, high-risk plaque; IPH, intraplaque haemorrhage; LRNC, lipid-rich necrotic core; MWT, mean wall thickness.