Table 3

Association between intracranial artery or carotid artery atherosclerotic diseases and ipsilateral ACI

	Presence of ipsilateral ACI
	Univariate regression			Multivariate regression*
	OR	95% CI	P value	OR	95% CI	P value
Intracranial artery stenosis ≥50%	3.090	1.757 to 5.432	<0.001	3.009	1.637 to 5.531	<0.001
Carotid stenosis ≥50%	2.799	1.297 to 6.041	0.009	2.561	1.116 to 5.878	0.026
Carotid MWT ≥1 mm	2.684	1.716 to 4.199	<0.001	2.495	1.521 to 4.093	<0.001
Carotid calcification	1.455	0.939 to 2.254	0.093	1.428	0.871 to 2.340	0.158
Carotid LRNC	1.553	0.996 to 2.421	0.052	1.273	0.776 to 2.090	0.340
Carotid IPH	1.369	0.680 to 2.756	0.379	1.745	0.802 to 3.799	0.160
Carotid HRP	0.959	0.532 to 1.730	0.890	0.986	0.511 to 1.901	0.967

*Adjusted for confounding factors of age, gender, body mass index, hypertension, diastolic blood pressure, high-density lipoprotein, total cholesterol, smoking and diabetes. The regression analysis for carotid FCR (fibrous cap rupture) was not applicable due to very few cases.
ACI, acute cerebral infarct; HRP, high-risk plaque; IPH, intraplaque haemorrhage; LRNC, lipid-rich necrotic core; MWT, mean wall thickness.