Demographic and clinical characteristics of the study cohort
| Characteristics | Mean(SD)/median (IQR)/n (%) n=61 |
| Age (years)* | 62.4±12.6 |
| Men (n, %) | 51 (83.6) |
| Hypertension (n, %) | 37 (60.7) |
| Diabetes mellitus (n, %) | 15 (24.6) |
| Smokers/ex-smokers (n, %) | 28 (45.9) |
| Atrial fibrillation (n, %) | 15 (24.6) |
| Previous stroke (n, %) | 11 (18.0) |
| OTT (minutes)* | 203.5±54.1 |
| NIHSS score on admission† | 9 (5–14) |
| SBP on admission (mm Hg)* | 150.6±22.8 |
| DBP on admission (mm Hg)* | 89.3±16.9 |
| NLR† | 2.4 (1.7–5.9) |
| BG level on admission(mmol/L)* | 7.0±2.3 |
| Homocysteine (mmol/L)* | 14.4±6.9 |
| END (n, %) | 20 (32.8) |
| Severe MCA stenosis (n, %) | 31 (50.8) |
| MCA occlusion (n, %) | 17 (27.9) |
| Severe ICA stenosis (n, %) | 4 (6.5) |
| ICA occlusion (n, %) | 9 (14.8) |
| DWI-ASPECT score† | 7 (5–8) |
| MHVs (n, %) | 35 (57.4) |
| Subtle (n, %) | 8 (13.1) |
| Moderate (n, %) | 23 (37.7) |
| Extensive (n, %) | 4 (6.6) |
| SVD burden† | 0 (0–1) |
*Mean±SD.
†Median (IQR).
ASPECT, Alberta Stroke Programme Early CT ; BG, blood glucose; DBP, diastolic blood pressure; DWI, diffusion-weighted imaging; END, early neurological deterioration; ICA, internal carotid artery; MCA, middle cerebral artery; MHVs, multiple hypointense vessels; NIHSS, National Institutes of Health Stroke Scale; NLR, neutrophil to lymphocyte ratio; OTT, onset to treatment time; SBP, systolic blood pressure; SVD, small vessel disease.