Table 4

National Institute of Health Stroke Scale (NIHSS) scores changed over time after intravenous thrombolysis

OutcomeWomen (n=541)Men (n=899)P valueAdjusted p value*
Median NIHSS on admission12.3±6.811.6±6.70.04
Median NIHSS 2 hours (±15 min)9.8±7.09.0±7.20.004
Median NIHSS 24 hours (±2 hour)9.1±8.38.3±7.90.07
Median NIHSS at discharge or 7 days (±1 day)6.7±7.86.2±7.00.41
Improving NIHSS 2 hours (±15 min)2.4±4.52.6±5.00.660.59
Improving NIHSS 24 hours (±2 hours)3.1±6.73.2±6.60.910.45
Improving NIHSS at discharge or 7 days (±1 day)5.2±7.15.0±6.70.200.33
  • *Adjusted baseline variables: age, diastolic blood pressure, current smoking, hypertension, diabetes mellitus, atrial fibrillation, antihypertensive agents before stroke, stroke-to-needle time, stroke-to-visit time, stroke-to-imaging time and Trial of Org 10172 in Acute Stroke Treatment (TOAST) types.

  • NIHSS, National Institute of Health Stroke Scale.