Baseline characteristics of patients with initial ischaemic stroke (n=12 415)
| Variable | Total (n=12 415) | Without GIB (n=12 093) | With GIB (n=322) | P value |
| Age, mean±SD (years) | 65.46±12.32 | 65.35±12.32 | 69.31±11.80 | <0.05 |
| Age category (years), n (%) | ||||
| <65 | 5500 (44.3) | 5403 (44.7) | 97 (30.1) | <0.05 |
| ≥65 | 6915 (55.7) | 6690 (55.3) | 225 (69.9) | <0.05 |
| Male, n (%) | 7658 (61.7) | 7453 (61.6) | 205 (63.5) | 0.459 |
| Baseline NIHSS, median (IQR) | 4 (2–9) | 4 (2–9) | 14 (6–22) | <0.05 |
| Hypertension, n (%) | 7909 (63.7) | 7687 (63.6) | 222 (68.9) | <0.05 |
| Hyperlipidaemia, n (%) | 1390 (11.2) | 1355 (11.2) | 35 (10.9) | 0.85 |
| Diabetes mellitus, n (%) | 2677 (21.6) | 2604 (21.5) | 73 (22.7) | 0.62 |
| Coronary heart disease, n (%) | 1792 (14.4) | 1729 (14.3) | 63 (19.6) | <0.05 |
| Atrial fibrillation, n (%) | 918 (7.4) | 881 (7.3) | 37 (11.5) | <0.05 |
| History of TIA, n (%) | 474 (3.8) | 464 (3.8) | 10 (3.1) | 0.50 |
| History of stroke, n (%) | 4234 (34.1) | 4085 (33.8) | 149 (46.3) | <0.05 |
| Family history of stroke, n (%) | 1519 (13.1) | 1468 (13.0) | 51 (15.8) | 0.05 |
| History of smoking, n (%) | 4934 (39.8) | 4808 (39.8) | 126 (39.1) | 0.82 |
| History of heavy alcohol use, n (%) | 1171 (9.4) | 1148 (9.5) | 23 (7.1) | 0.15 |
| Antithrombotic therapy, n (%) | 2067 (16.6) | 2003 (16.6) | 64 (19.9) | 0.12 |
| Pneumonia, n (%) | 1439 (11.6) | 1244 (10.3) | 195 (60.6) | <0.05 |
| Urinary tract infection, n (%) | 474 (3.8) | 431 (3.6) | 43 (13.4) | <0.05 |
GIB, gastrointestinal bleeding; NIHSS, National Institute of Health Stroke Scale; TIA, transient ischaemic attack.