Table 3

Summary of intrasaccular flow disruption devices

Intrasaccular flow disruption devicesAuthor, yearPatients, aneurysms (n)Aneurysm locationOcclusion rateMorbidity (%), mortality (%)
WEB deviceKlisch et al, 201186 2, 2Unruptured basilar tip and unruptured MCA bifurcaton100% at 8 weeks0, 0
Mine et al, 201891 48, 4929/49 (59%) located on the MCA, 7/49 on the basilar tip (14%), 5/49 on the ICA (10%), 5/49 ACoA (10%), 2/49 on the PICA (4%) and 1/49 on the vertebral artery (2%)72.3% 34/47 (range 3–72 months, mean 25 months, median 24 months)8.3, 0
Arthur et al, 2019 (WEB-IT Study)88 150, 150 (148 successfully delivered)Wide-necked bifurcation aneurysms53.8% complete occlusion, 84.6% complete occlusion/residual neck at 1 year0.7, 0
Popielski et al, 2018105 102, 10186.3% anterior and 13.7% posterior ruptured and unruptured aneurysms80.7% (63/78) at 3 months and 77.6% (38/49) at 12 months4, 1
Kaya et al, 202092 42; 42MCA bifurcation in 29 (69%), basilar tip in 5 (12%), ACoA in 5 (12%), ICA tip in 2 (5%), and M1 segment of MCA in 1 (2%) patientAdequate occlusion (complete or neck remnant) in 97.0% (35/36) at 1 year0, 0
Goertz et al, 201998 20; 20ICA sidewall aneurysms paraophthalmic segment (n=10), the posterior communicating artery segment (n=9) and the anterior choroidal artery segment (n=1)76.5% at a mean of 9.6±8.2 months0, 0
WEB 17van Rooij et al, 201894 40; 46ACoA in 17, MCA in 13, PICA in 7; pericallosal artery in 3; basilar tip in 3; and the anterior choroidal artery, carotid tip and superior cerebellar artery each in 172% at 3 months0, 0
Maurer et al, 201995 117; 12726.0% ACoA, 8.6% ACA, 41.0% MCA bifurcation, 1.6% MCA M1, 7.8% ICA PComA, 4.0% ICA bifurcation, 5.4% basilar tip, 0.8% PCA, 2.4% PICA, 2.4% superior cerebellar artery76.1% (70/92) at 3 months and 78.0% (32/41) 12 months.1.7, 0
LUNA AESPiotin et al, 2018101 63; 6423.4% ACoA, 6.3% basilar apex, 29.7 MCA, 12.5% ICA terminus, 4.7% ICA (cavernous), 4.7% ICA (ophthalmic), 4.7% ICA (PComm), 4.7% ICA (hypophyseal), 4.7% PCA, 3.1% ACA, 1.6% PICAAdequate occlusion in 78.0% in 1 year and 79.2% in 3 years1.6, 1.6
  • ACA, anterior cerebral artery; ACoA, anterior communicating artery; ICA, internal carotid artery; MCA, middle cerebral artery; PCA, posterior cerebral artery; PComm, posterior communicating artery; PICA, posterior inferior cerebellar artery; WEB, Woven EndoBridge.