Table 1

Technical specifications for flow diverters

Flow diverterPipeline (PED)Pipeline FlexPipeline ShieldSurpassSilkSilk+Silk Vista BabyFREDFRED Jr.p64DerivoTubridgeFloWise
CE (Europe) approval20082014201520112008201220182012201520122013Not reportedNot reported
FDA approval20112015N/A2018N/AN/AN/A20192019N/AN/AN/AN/A
Material25% platinum-tungsten; 75% cobalt-chromium25% platinum-tungsten; 75% cobalt-chromium25% platinum-tungsten; 75% cobalt-chromium-nickel alloyCobalt-chromium92% Nitinol; 8% PlatinumNitinol, platinumNitinol, platinumNitinolNitinol, tantalumNitinolNitinolNitinol, patinum-iridiumNitinol, platinum
Number of braids48484848-96484848645264486448
GenerationFirstSecondThirdFirstFirstSecondThirdFirstSecondFirstFirstFirstFirst
Delivery systemEmpty catheter via 0.027-inch microcatheterEmpty catheter via 0.027-inch microcatheterEmpty catheter via 0.027-inch microcatheterPreloaded over-the-wire delivery system with a 0.040″ inner diameter delivery micocatheter and pusherEmpty catheter via 0.021, 0.023- or 0.025-inch microcatheterEmpty catheter via 0.021-, 0.023- or 0.025-inch microcatheterEmpty catheter via 0.017-inch microcatheterEmpty catheter via 0.027-inch microcatheterEmpty catheter via 0.021-inch microcatheterEmpty catheter via 0.027-inch microcatheterEmpty catheter via 0.027-inch microcatheterEmpty catheter via 0.029-inch microcatheterEmpty catheter via 0.027-inch microcatheter
Resheath featureNoYesYesYesYesYesYesYesYesYesYesYesYes
Occlusion rate81.8-93.3% at 6 months77% at 12 mo78.8-90.3% 6-18 mo62-94% 6-12 mo68% at 6 mo, up to 93.9% at 12 mo73% (mean 22 mo)63% (mean 2.7 mo)73% 6 mo, up to 96% 12-24 mo87% (6-24 mo)66% at 6 mo; up to 98.5% at 24 mo80.7% at 6 mo; 89.2% at 12 mo75.34% at 6 mo66.7% at 6 mo
  • FDA, Food and Drug Administration; FRED, Flow-Redirection Endoluminal Device; N/A, not applicable; PED, Pipeline Embolization Device.