Summary of intrasaccular flow disruption devices
| Intrasaccular flow disruption devices | Author, year | Patients, aneurysms (n) | Aneurysm location | Occlusion rate | Morbidity (%), mortality (%) |
| WEB device | Klisch et al, 201186 | 2, 2 | Unruptured basilar tip and unruptured MCA bifurcaton | 100% at 8 weeks | 0, 0 |
| Mine et al, 201891 | 48, 49 | 29/49 (59%) located on the MCA, 7/49 on the basilar tip (14%), 5/49 on the ICA (10%), 5/49 ACoA (10%), 2/49 on the PICA (4%) and 1/49 on the vertebral artery (2%) | 72.3% 34/47 (range 3–72 months, mean 25 months, median 24 months) | 8.3, 0 | |
| Arthur et al, 2019 (WEB-IT Study)88 | 150, 150 (148 successfully delivered) | Wide-necked bifurcation aneurysms | 53.8% complete occlusion, 84.6% complete occlusion/residual neck at 1 year | 0.7, 0 | |
| Popielski et al, 2018105 | 102, 101 | 86.3% anterior and 13.7% posterior ruptured and unruptured aneurysms | 80.7% (63/78) at 3 months and 77.6% (38/49) at 12 months | 4, 1 | |
| Kaya et al, 202092 | 42; 42 | MCA bifurcation in 29 (69%), basilar tip in 5 (12%), ACoA in 5 (12%), ICA tip in 2 (5%), and M1 segment of MCA in 1 (2%) patient | Adequate occlusion (complete or neck remnant) in 97.0% (35/36) at 1 year | 0, 0 | |
| Goertz et al, 201998 | 20; 20 | ICA sidewall aneurysms paraophthalmic segment (n=10), the posterior communicating artery segment (n=9) and the anterior choroidal artery segment (n=1) | 76.5% at a mean of 9.6±8.2 months | 0, 0 | |
| WEB 17 | van Rooij et al, 201894 | 40; 46 | ACoA in 17, MCA in 13, PICA in 7; pericallosal artery in 3; basilar tip in 3; and the anterior choroidal artery, carotid tip and superior cerebellar artery each in 1 | 72% at 3 months | 0, 0 |
| Maurer et al, 201995 | 117; 127 | 26.0% ACoA, 8.6% ACA, 41.0% MCA bifurcation, 1.6% MCA M1, 7.8% ICA PComA, 4.0% ICA bifurcation, 5.4% basilar tip, 0.8% PCA, 2.4% PICA, 2.4% superior cerebellar artery | 76.1% (70/92) at 3 months and 78.0% (32/41) 12 months. | 1.7, 0 | |
| LUNA AES | Piotin et al, 2018101 | 63; 64 | 23.4% ACoA, 6.3% basilar apex, 29.7 MCA, 12.5% ICA terminus, 4.7% ICA (cavernous), 4.7% ICA (ophthalmic), 4.7% ICA (PComm), 4.7% ICA (hypophyseal), 4.7% PCA, 3.1% ACA, 1.6% PICA | Adequate occlusion in 78.0% in 1 year and 79.2% in 3 years | 1.6, 1.6 |
ACA, anterior cerebral artery; ACoA, anterior communicating artery; ICA, internal carotid artery; MCA, middle cerebral artery; PCA, posterior cerebral artery; PComm, posterior communicating artery; PICA, posterior inferior cerebellar artery; WEB, Woven EndoBridge.