Table 5

Sex-specific associations with good outcomes

VariableWomenMen
UnivariableMultivariableUnivariableMultivariable
EstimateP valuesEstimateP valuesEstimateP valuesEstimateP values
Age−0.010.40−0.05 0.006
BMI0.070.180.040.31
Anticoagulant use0.50.560.30.57
Atrial fibrillation−0.10.88−1.00.06
Diabetes−1.10.200.030.95
Hyperlipidaemia0.10.92−0.40.34
Hypertension0.70.17−1.00.06
Prior stroke/TIA−1.20.10−0.70.16
Cardioembolic stroke0.10.880.10.80
Admission NIHSS−0.3 < 0.001 −0.2 < 0.001
Systolic blood pressure−0.010.93−0.010.44
IV alteplase treatment−0.50.36−1.4 0.002 −1.3 0.01
HT0.020.97−0.60.20
WMHv−0.10.07−0.2 0.02
DWIv−0.03 0.04 −0.030.05−0.04 0.006 −0.04 0.01
NAWM ADC−0.01 0.03 −0.01 0.04 −0.02 0.0007 −0.02 0.003
NAWM K 2 −0.00040.06−0.00010.42
  • Multivariable Regression Equation.

  • Bold values indicate P value < 0.05.

  • ADC, apparent diffusion coefficient; BMI, body mass index; DWIv, diffusion-weighted imaging lesion volume; HT, haemorrhagic transformation; IV, intravenous; NAWM, normal-appearing white matter; TIA, transient ischemic attack; WMHv, white matter hyperintensity volume.