Table 4

Sex-specific associations with acute infarct volume

Variable	Women				Men
	Univariable		Multivariable		Univariable
	Estimate	P values	Estimate	P values	Estimate	P values
Age	−0.1	0.60			0.3	0.20
BMI	−0.55	0.25			−0.84	0.21
Anticoagulant use	−4.5	0.61			−6.5	0.45
Atrial fibrillation	−1.2	0.84			20.8	0.01
Diabetes	−11.8	0.14			−3.6	0.64
Hyperlipidaemia	0.6	0.92			−6.4	0.34
Hypertension	−5.7	0.36			12.8	0.09
Prior stroke/TIA	6.1	0.38			13.7	0.07
Cardioembolic stroke	1.8	0.76			−1.1	0.87
Admission NIHSS	2.7	<0.001			3.0	<0.001
Systolic blood pressure	−0.1	0.48			0.02	0.85
IV alteplase treatment	13.3	0.03	12.6	0.03	7.8	0.27
HT	20.6	0.005	16.9	0.01	13.0	0.11
WMHv	0.3	0.43			0.13	0.84
NAWM ADC	0.02	0.66			0.08	0.24
NAWM K₂	0.006	0.01	0.007	0.01	−0.001	0.50
NAWM mask volume	0.15	0.54			−0.1	0.78

Multivariable Regression Equation.
Men:NA.
Bold values indicate P value < 0.05.
ADC, apparent diffusion coefficient; BMI, body mass index; DWIv, diffusion-weighted imaging lesion volume; HT, haemorrhagic transformation; IV, intravenous; NA, not applicable; NAWM, normal-appearing white matter; NIHSS, National Institutes of Health Stroke Scale; TIA, transient ischemic attack; WMHv, white matter hyperintensity volume.