Functional outcome and death at day 90 by degree of ipsilateral carotid stenosis
| Stenosis <30% | Stenosis 30–<50% | Stenosis 50–<70% | Stenosis ≥70% | |||||||
| n (%) /median [IQR] | OR (95% CI) | P value | n (%) /median [IQR] | OR (95% CI) | P value | n (%) /median [IQR] | OR (95% CI) | P value | ||
| Number of participants | 1431 | 224 | – | – | 148 | – | – | 213 | – | – |
| mRS (/6)* | 2 [3] | 2 [2] | 1.03 (0.80 to 1.33) | 0.83 | 3 [2] | 1.21 (0.89 to 1.64) | 0.23 | 3 [2] | 1.88 (1.44 to 2.44) | <0.001 |
| Death (%) | 67 (4.7) | 21 (9.4) | 1.85 (1.06 to 3.22) | 0.030 | 11 (7.4) | 1.43 (0.71 to 2.90) | 0.32 | 25 (11.8) | 2.52 (1.48 to 4.27) | 0.001 |
Data are n (%), median (IQR) or OR with 95% CIs. Comparison using logistic or ordinal regression with <30% stenosis as reference group. Adjusted for age, sex, baseline mRS, history of previous stroke, history of diabetes mellitus, TACS, nitrate use, baseline SSS, thrombolysis, feeding status, time to randomisation, baseline SBP, GTN/no GTN and continue/stop.
*Ordinal logistic regression.
GTN, glyceryl trinitrate; mRS, modified Rankin Scale; SSS, Scandinavian Stroke Scale.