Baseline NIHSS score and outcome of 601 treated with intravenous tPA
| ≤4.5 hours (n=327） | 4.5 hours~12 hours (n=274） | P value | |
| Baseline NIHSS | 10.86±4.83 | 10.98±4.10 | 0.182 |
| 24 hours NIHSS | 6.73±4.27 | 7.08±4.93 | 0.626 |
| 7 day NIHSS | 5.05±4.23 | 5.68±4.96 | 0.515 |
| Arterial stenosis (%) | 26.90 (88/327) | 25.91 (71/274) | 0.534 |
| Recanalisation (%) | 42.05 (37/88) | 38.57 (27/70） | 0.415 |
| Asymptomatic ICH (%) | 3.98 (13/327) | 4.74 (13/274) | 0.324 |
| Symptomatic ICH (%) | 0.92 (3/327) | 1.09 (3/274) | 0.526 |
| Death (%) | 0.72 (2/327) | 0.73 (2/274) | 0.583 |
| 90-day mRS (0 or 1) or NIHSS improved ≥8 (%) | 86.85 (284/327) | 85.04 (233/274) | 0.679 |
| 90-day BI (≥95) (%) | 83.20 (272/327) | 80.29 (220/274) | 0.541 |
BI, Barthel Index; ICH, intracranial haemorrhage; NIHSS, National Institutes of Health Stroke Scale; tPA, tissue plasminogen activator.