Table 3

Standard time window: predictive factor analysis for good outcome (mRS 0–1)

MonofactorMultifactor*
OR (95% CI)P valueOR (95% CI)P value
Age (year)0.99 (0.97 to 1.02)0.6560.97 (0.94 to 1.01)0.097
Gender0.99 (0.53 to 1.87)0.9840.60 (0.27 to 1.33)0.208
Hypertension0.45 (0.23 to 0.87)0.0180.65 (0.29 to 1.46)0.299
Diabetes1.21 (0.55 to 2.66)0.6332.73 (0.92 to 8.11)0.072
Hyperlipaemia0.97 (0.55 to 1.71)0.9051.04 (0.51 to 2.10)0.919
AF2.41 (0.54 to 10.73)0.248
Stroke0.40 (0.05 to 3.22)0.389
SBP/5 mm Hg0.93 (0.87 to 0.99)0.0330.94 (0.87 to 1.03)0.180
DBP/5 mm Hg0.94 (0.84 to 1.05)0.241
FBG (mmol/L)0.86 (0.77 to 0.97)0.0110.81 (0.70 to 0.95)0.009
GHb0.90 (0.77 to 1.05)0.186
TG (mmol/L)1.20 (0.91 to 1.58)0.206
TC (mmol/L)0.66 (0.52 to 0.85)0.0010.62 (0.36 to 1.05)0.073
LDL-C (mmol/L)0.73 (0.55 to 0.97)0.0321.25 (0.69 to 2.29)0.465
UA (μmol/L)1.00 (1.00 to 1.00)0.849
Fg1.01 (0.72 to 1.41)0.977
Hcy (µmol/L)0.98 (0.96 to 1.01)0.200
Admission NIHSS0.80 (0.75 to 0.86)<0.0010.79 (0.73 to 0.85)<0.001
DTN (hour)1.00 (0.74 to 1.36)0.9961.13 (0.78 to 1.65)0.515
  • *Adjusted age, gender, hypertension, diabetes, hyperlipaemia, TOAST, SBP, FBG, TC, LDL-C, admission NIHSS and DTN.

  • AF, atrial fibrillation; DBP, diastolic blood pressure; DTN, door-to-needle time; FBG, fasting blood glucose; Fg, fibrinogen; GHb, glycosylated haemoglobin; Hcy, homocysteine; LDL-C, low-density lipoprotein cholesterol; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressur; TC, total cholesterol; TG, triglyceride; TOAST, design of the trial of Org 10172 in acute stroke treatment;  UA, uric acid.