Analysis of non-intracranial haemorrhagic events
| Minor stroke | TIA | Overall | ||||
|---|---|---|---|---|---|---|
| Covariate | Aspirin (n=1858) | Clopidogrel–aspirin (n=1867) | Aspirin (n=728) | Clopidogrel–aspirin (n=717) | Aspirin (n=2586) | Clopidogrel–aspirin (n=2584) |
| Total | 23 (1.24%) | 46 (2.46%) | 18 (2.47%) | 14 (1.95%) | 41 (1.59%) | 60 (2.32%) |
| Epistaxis | 1 (0.05%) | 3 (0.16%) | 2 (0.27%) | 1 (0.14%) | 3 (0.12%) | 4 (0.15%) |
| Gastrointestinal bleeding | 4 (0.22%) | 6 (0.32%) | 1 (0.14%) | 2 (0.28%) | 5 (0.19%) | 8 (0.31%) |
| Gum bleeding | 1 (0.05%) | 4 (0.21%) | 4 (0.55%) | 0 (0.00%) | 5 (0.19%) | 4 (0.15%) |
| Haemoptysis | 0 (0.0%) | 0 (0.0%) | 0 (0.00%) | 1 (0.14%) | 0 (0.00%) | 1 (0.04%) |
| Intraocular haemorrhage | 1 (0.05%) | 4 (0.21%) | 2 (0.27%) | 1 (0.14%) | 3 (0.12%) | 5 (0.19%) |
| Intracranial haemorrhage | 12 (0.65%) | 17 (0.91%) | 4 (0.55%) | 3 (0.42%) | 16 (0.62%) | 20 (0.77%) |
| Oral haemorrhage | 1 (0.05%) | 0 (0.00%) | 0 (0.0%) | 0 (0.0%) | 1 (0.04%) | 0 (0.00%) |
| Puncture site bleeding | 0 (0.0%) | 0 (0.0%) | 1 (0.14%) | 0 (0.00%) | 1 (0.04%) | 0 (0.00%) |
| Skin bruises | 3 (0.16%) | 11 (0.59%) | 4 (0.55%) | 6 (0.84%) | 7 (0.27%) | 17 (0.66%) |
| Vaginal bleeding | 0 (0.00%) | 1 (0.05%) | 0 (0.0%) | 0 (0.0%) | 0 (0.00%) | 1 (0.04%) |
TIA, transient ischaemic attack.