Demographic and clinical characteristics of the study population at baseline
| Variables | All patients | Groups | ||
| (n=1062) | Insomnia (n=489) | Non-insomnia (n=573) | P value | |
| Demographic characteristics | ||||
| Age, year, mean±SD | 60.47±11.57 | 48.9±46.0 | 57.3±54.0 | 0.08 |
| Female, n (%) | 364 (34.3) | 195 (39.9) | 169 (29.5) | <0.001 |
| Education level, n (%) | ||||
| High school and above, n (%) | 762 (72.0) | 351 (71.8) | 411 (72.1) | 0.25 |
| Married, n (%) | 992 (93.5) | 456 (93.3) | 536 (93.5) | 0.90 |
| Living alone, n (%) | 25 (2.4) | 9 (1.84) | 16 (2.8) | 0.42 |
| Employed, n (%) | 502 (47.4) | 215 (44.1) | 287 (50.4) | 0.04 |
| Family history of mental disease, n (%) | 188 (18.3) | 87 (18.2) | 101 (18.3) | 1.0 |
| Vascular risk factors | ||||
| Smoker, n (%) | 483 (45.7) | 216 (44.3) | 267 (46.9) | 0.42 |
| Hypertension, n (%) | 708 (67.9) | 321 (66.7) | 387 (68.9) | 0.47 |
| Diabetes, n (%) | 224 (21.5) | 105 (21.9) | 119 (21.2) | 0.82 |
| Hyperlipidaemia, n (%) | 179 (19.0) | 80 (18.3) | 99 (19.8) | 0.62 |
| Clinical characteristics | ||||
| Diagnosis of ISH, n (%) | 863 (81.3) | 383 (78.3) | 480 (83.8) | 0.02 |
| NIHSS score at 14±2 day, mean±SD | 4.62±4.03 | 5.21±4.4 | 4.12±3.7 | <0.001 |
| Depression at 1-year follow-up, n (%) | 387 (36.4) | 268 (54.8) | 119 (20.8) | <0.001 |
| Stroke recurrence at 1-year follow-up, n (%) | 65 (6.1) | 40 (8.2) | 25 (4.4) | 0.02 |
| Death at 6-year follow-up, n (%) | 130 (12.2) | 74 (15.1) | 56 (9.7) | 0.008 |
Smoker, with or without a history of smoking.
ISH, ischaemic stroke; NIHSS score, the first National Institutes of Health Stroke Scale.