TY - JOUR T1 - Residual recurrence risk of ischaemic cerebrovascular events: concept, classification and implications JF - Stroke and Vascular Neurology JO - Stroke Vasc Neurol DO - 10.1136/svn-2021-000885 SP - svn-2021-000885 AU - Yongjun Wang Y1 - 2021/03/16 UR - http://svn.bmj.com/content/early/2021/03/16/svn-2021-000885.abstract N2 - Patients with stroke still have substantial residual risk of stroke recurrence in spite of therapies following the guidelines.1 In addition to traditional vascular risk factors, conditions such as chronic inflammation, poor quality of care and variable response to standard therapy may contribute to the residual risk of stroke recurrence.2–4 Therefore, it is important to understand and classify the sources of residual risk to improve the prevention of stroke recurrence in patients already have a stroke.Conceptualisation and classification of the residual riskResidual risk is the amount of risk that remains after management or elimination of the known risk factors. Globally, the residual recurrence risk in patients who has a stroke has not been well estimated and varies between 3% and 6%.1 5 6 From the perspective of clinical practice, residual risk could be classified into three types:Care-quality-based residual riskSuch type of residual risk developed mainly because of poor individual adherence to treatment. Though secondary prevention measures such as the use of antithrombotic, antihypertensive, anti diabetic and lipid-lowering agents plus lifestyle modification have been recommended, adherence to these evidence-based therapies may be suboptimal in the real world,7 A multifaceted care quality intervention to improve adherence to guideline-based performance measures and secondary prevention … ER -