RT Journal Article
SR Electronic
T1 Intracerebral haemorrhage: from clinical settings to animal models
JF Stroke and Vascular Neurology
JO Stroke Vasc Neurol
FD BMJ Publishing Group Ltd
SP 388
OP 395
DO 10.1136/svn-2020-000334
VO 5
IS 4
A1 Qian Bai
A1 Zhaofu Sheng
A1 Yang Liu
A1 Ruiyi Zhang
A1 Voon Wee Yong
A1 Mengzhou Xue
YR 2020
UL http://svn.bmj.com/content/5/4/388.abstract
AB Spontaneous intracerebral haemorrhage (ICH) is a devastating type of stroke with high mortality and morbidity and for which no effective treatments are available to date. Much experimental and clinical research have been performed to explore its mechanisms regard the subsequent inflammatory cascade and to seek the potential therapeutic strategies. The aim of this review is to discuss insights from clinical settings that have led to the development of numerous animal models of ICH. Some of the current and future challenges for clinicians to understand ICH are also surveyed.