RT Journal Article
SR Electronic
T1 Lower lymphocyte to monocyte ratio is a potential predictor of poor outcome in patients with cerebral venous sinus thrombosis
JF Stroke and Vascular Neurology
JO Stroke Vasc Neurol
FD BMJ Publishing Group Ltd
SP 148
OP 153
DO 10.1136/svn-2018-000180
VO 4
IS 3
A1 Shen Li
A1 Kai Liu
A1 Rui Zhang
A1 Yuan Gao
A1 Hui Fang
A1 Xinjing Liu
A1 Lulu Pei
A1 L-Ying Richard Chou
A1 Sheng Guan
A1 Xinbin Guo
A1 Haowen Xu
A1 Bo Song
A1 Yuming Xu
YR 2019
UL http://svn.bmj.com/content/4/3/148.abstract
AB Background Lymphocyte to monocyte ratio (LMR) is associated with functional outcome in patients with stroke. But the relationship between the LMR value and the prognosis of cerebral venous sinus thrombosis (CVST) has not been investigated.Methods CVST patients, admitted to the First Affiliated Hospital of Zhengzhou University, were retrospectively identified from November 2010 to January 2017. Functional outcomes of patients were evaluated with the modified Rankin Scale (mRS). Patients were divided into good (mRS 0–2) and poor (mRS 3–6) outcomes groups. Univariate and multivariate Cox regression analyses were used to assess the relationship between LMR and the poor survival outcome.Results A total of 228 patients were included of which 41 had poor outcomes (18.0%). The duration of follow-up was 22 months (6–66 months). LMR (2.3±1.2 vs 3.2±1.8, p<0.01) was significantly lower in the poor outcome group. Multivariate Cox regression analysis showed that LMR (HR 0.726, 95% CI 0.546 to 0.964, p=0.027) was a independent predictor of poor prognosis.Conclusions LMR may be a predictor of poor prognosis in CVST patients.