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Rationale and design of Patient-centered Retrospective Observation of Guideline-Recommended Execution for Stroke Sufferers in China: China PROGRESS
  1. Zixiao Li1,2,3,4,
  2. Chunjuan Wang2,3,4,
  3. Yong Jiang2,3,4,
  4. Xinmiao Zhang1,3,4,
  5. Ying Xian5,
  6. Liping Liu2,3,4,6,
  7. Xingquan Zhao1,2,3,4,
  8. Hongqiu Gu2,3,4,
  9. Xia Meng2,3,4,
  10. Hao Li2,3,4,
  11. Yilong Wang1,2,3,4,
  12. Yongjun Wang1,2,3,4
  1. 1 Vascular Neurology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  2. 2 China National Clinical Research Center for Neurological Diseases, Beijing, China
  3. 3 Center of Stroke, Beijing Institute for BrainDisorders, Beijing, China
  4. 4 Beijing Key Laboratory of Translational Medicine forCerebrovascular Disease, Beijing, China
  5. 5 Duke Clinical Research Institute, North Carolina, USA
  6. 6 Neuro-intensive Care Unit, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  1. Correspondence to Dr Yongjun Wang, Vascular Neurology, Department of Neurology Beijing Tiantan Hospital, Capital Medical University Beijing China; yongjunwang{at}ncrcnd.org.cn

Abstract

Background In 2009, China launched ambitious healthcare reform plans to provide affordable and equitable basic healthcare for all patients, including the substantial number of patients who had a stroke. However, little is known about the pattern of evidence-based stroke care and outcomes across hospitals, regions and time during the last decade.

Aims The Patient-centered Retrospective Observation of Guideline-Recommended Execution for Stroke Sufferers in China (China PROGRESS) Study aims to use findings from a representative sample of Chinese hospitals over the last decade to improve future stroke care for patients hospitalised with ischaemic stroke (IS) or transient ischaemic attack (TIA).

Design The China PROGRESS Study will use a two-stage cluster sampling method to identify over 32000 patient records from 208 hospitals across the Eastern, Central and Western geographical regions in China. To assess the temporal trends in patient characteristics, treatment and outcomes, study investigators will select records from 2005, 2010 and 2015. A double data reading/entry system will be developed to conduct this assessment. A central coordinating centre will monitor case ascertainment, data abstraction and data management. Analyses will examine patient characteristics, testing patterns, in-hospital treatment and outcomes, and variations across regions and across time.

Conclusions The China PROGRESS Study is the first nationally representative study that aims to better understand care quality and outcomes for patients with IS or TIA before and after the national healthcare reform in China. This initiative will translate findings into clinical practices that improve care quality for patients who had a stroke and policy recommendations that allow these changes to be implemented widely.

Ethics approval

This study has also been approved by the central institutional review board (IRB) at Beijing Tiantan Hospital.

  • quality of care
  • acute ischemic stroke
  • epidemiology
  • mortality

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

https://doi.org/10.1136/svn-2019-000233

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    Footnotes

    • ZL, CW and YJ contributed equally.

    • Contributors ZL, JY, XinmZ, YX, XingZ, HG, HL, YiW and YoW conceived the study and oversaw all scientific aspects of its implementation. ZL, CW and JY drafted the manuscript. HG conducted the data analysis. CW, XinmZ, LL and XM recruited hospitals and operated the China PROGRESS programme.

    • Funding This work was supported by grants from the National Key R&D Program of China (2017YFC1310901, 2016YFC0901002, 2016YFC0901001), Beijing Municipal Committee of Science and Technology (D151100002015003), Beijing Municipal Administration of Hospitals’ Mission Plan (SML20150502) and Beijing BaiQianWan Talents Program.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Data sharing statement Data are available upon reasonable request.

    • Patient consent for publication Not required.