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Review
Coagulopathy reversal in intracerebral haemorrhage
  1. Alexander Jacob Sweidan1,
  2. Navneet Kaur Singh2,
  3. Joseph Luke Conovaloff1,
  4. Matthew Bower1,
  5. Leonid I Groysman1,
  6. Mohammad Shafie1,
  7. Wengui Yu1
  1. 1 Neurology, University of California Irvine Medical Center, Orange, California, USA
  2. 2 Medicine, University of California Irvine Medical Center, Orange, California, USA
  1. Correspondence to Dr Alexander Jacob Sweidan; ASweidan{at}UCI.edu

Abstract

As intracerebral hemorrahge becomes more frequent as a result of an aging population with greater comorbidities, rapid identification and reversal of precipitators becomes increasingly paramount. The aformentioned population will ever more likely be on some form of anticoagulant therapy. Understanding the mechanisms of these agents and means by which to reverse them early on is critical in managing the acute intracerebral hemorrhage.

  • anticoagulation
  • cerebral hemorrhage
  • hemorrhagic stroke
  • coagulopathy reversal
http://creativecommons.org/licenses/by-nc/4.0/

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

https://doi.org/10.1136/svn-2019-000274

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    Footnotes

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    • Contributors AS and NS contributed to drafting, revising and finalising the manuscript. JC revised the manuscript critically for important intellectual content and prepared tables. MB, LG and MS revised critically for important intellectual content. WY revised critically for important intellectual content and finalised the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Not required.

    • Provenance and peer review Commissioned; externally peer reviewed.