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Review
Red blood cell distribution width and ischaemic stroke
  1. Gang-Hua Feng1,
  2. Hai-Peng Li1,
  3. Qiu-Li Li1,
  4. Ying Fu2,
  5. Ren-Bin Huang1
  1. 1 Department of Neurology, The First People’s Hospital of Chenzhou, University of South China, Chenzhou, China
  2. 2 Thyroid Medicine Department/Radionuclide Therapy Department (Ward 31), Hunan Provincial Tumor Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China
  1. Correspondence to Professor Ren-Bin Huang; 470165013{at}qq.com

Abstract

The red blood cell distribution width (RDW) is a measure of red blood cell (RBC) size heterogeneity, which is easily calculated by dividing the SD of erythrocyte volumes for the mean corpuscular volume. Recent reporter suggested that, besides haematological diseases and anaemia, many human disorders may be closely associated with the elevated RDW. A literature review has revealed the RDW may be closely related to the development of ischaemic stroke, carotid artery atherosclerosis and cerebral embolism. Higher RDW could independently predict adverse outcomes in patients in these conditions.

  • Red blood cell distribution width (RDW)
  • ischaemic stroke
  • cerebral embolism
  • carotid artery atherosclerosis (CAS)

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

https://doi.org/10.1136/svn-2017-000071

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    Footnotes

    • Contributors FF and RH conceived this study. HL provided technical supports. QL conducted statistical analysis and interpreted the data. FF drafted this manuscript and JB and ZL made critical revisions. HL supervised this study.

    • Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Data sharing statement No additional unpublished data are available.