… Nikola Sprigg … Nikola Sprigg Nikola Sprigg …

Post-stroke dysphagia (a difficulty in swallowing after a stroke) is a common and expensive
complication of acute stroke and is associated with increased mortality, morbidity, and …

… In those with a history of cerebrovascular disease in HPS (n=3,280), simvastatin was
associated with a 20% reduction in major cardiovascular events compared with placebo, but there …

… Structurally, the SOCS proteins are composed of an N-terminal region of variable length …
These proteins fall into five classes based on the protein motifs found N-terminal of the SOCS …

Mice lacking suppressor of cytokine signaling-1 (SOCS1) develop a complex fatal neonatal
disease. In this study, SOCS1 −/− mice were shown to exhibit excessive responses typical of …

Background Tranexamic acid can prevent death due to bleeding after trauma and post-partum
haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma …

Background High blood pressure is common in acute stroke and is a predictor of poor
outcome; however, large trials of lowering blood pressure have given variable results, and the …

Background Early control of elevated blood pressure is the most promising treatment for
acute intracerebral haemorrhage. We aimed to establish whether implementing a goal-directed …

Background Antiplatelet therapy reduces the risk of major vascular events for people with
occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. …

Background Intensive antiplatelet therapy with three agents might be more effective than
guideline treatment for preventing recurrent events in patients with acute cerebral ischaemia. …