Demographic and clinical characteristics of the study population at baseline
| Variables | All patients | Groups | ||
| (n=1062) | Death (n=130) | Survivors (n=932) | P value | |
| Demographic characteristics | ||||
| Age, year, mean±SD | 60.47±11.57 | 69.7±11.0 | 59.2±11.0 | 0.00 |
| Female, n (%) | 364 (34.3) | 51 (39.2) | 313 (33.6) | 0.20 |
| Education level, n (%) | ||||
| High school and above, n (%) | 762 (71.8) | 76 (58.5) | 686 (73.6) | 0.00 |
| Married, n (%) | 992 (93.4) | 118 (90.8) | 874 (93.8) | 0.20 |
| Living alone, n (%) | 25 (2.4) | 6 (4.6) | 19 (2.0) | 0.07 |
| Employed, n (%) | 502 (47.5) | 28 (21.5) | 474 (51.2) | 0.00 |
| Family history of mental disease, n (%) | 188 (18.3) | 15 (12.3) | 173 (19.1) | 0.07 |
| Vascular risk factors | ||||
| Smoker, n (%) | 483 (45.7) | 45 (35.2) | 438 (47.2) | 0.01 |
| Hypertension, n (%) | 708 (67.9) | 99 (76.2) | 614 (66.7) | 0.03 |
| Hyperlipidaemia, n (%) | 179 (19.1) | 17 (14.8) | 162 (19.8) | 0.20 |
| Diabetes, n (%) | 224 (21.5) | 33 (26.2) | 191 (20.9) | 0.17 |
| Clinical characteristics | ||||
| Diagnosis of ISH, n (%) | 863 (81.3) | 111 (78.3) | 752 (85.4) | 0.21 |
| NIHSS score at 14±2 days, mean±SD | 4.62±4.03 | 5.23±4.0 | 4.54±4.0 | 0.07 |
| Depression at 1-year follow-up, n (%) | 387 (36.4) | 49 (37.7) | 338 (36.3) | 0.75 |
| Stroke recurrence at 1-year follow-up, n (%) | 65 (6.1) | 19 (14.6) | 47 (5.0) | 0.00 |
| Insomnia, n (%) | 489 (46.0) | 74 (56.9) | 415 (44.5) | 0.01 |
| Difficulty falling asleep, n (%) | 69 (6.5) | 14 (10.8) | 55 (5.9) | 0.04 |
| Difficulty staying asleep, n (%) | 19 (4.8) | 7 (5.4) | 12 (1.3) | 0.001 |
| Waking up early, n (%) | 44 (4.2) | 6 (4.6) | 38 (4.2) | 0.82 |
| Difficulty falling asleep and staying asleep, n (%) | 52 (4.9) | 7 (5.4) | 45 (4.8) | 0.78 |
| Difficulty falling asleep and waking up early, n (%) | 73 (6.9) | 10 (7.7) | 63 (6.8) | 0.69 |
| Difficulty staying asleep and waking up early, n (%) | 24 (2.3) | 3 (2.3) | 21 (2.3) | 0.97 |
| All of the three, n (%) | 208 (19.8) | 27 (21.5) | 181 (19.5) | 0.59 |
Smoker, with or without a history of smoking.
ISH, ischaemic stroke; NIHSS score, the first National Institutes of Health Stroke Scale.