Characteristics of studies included in the review
| Publication | Origin | Cases | Definition | Time to needle (hours) | Age | Men | Definition of sICH | Baseline NIHSS score | mRS 0–1 at 3 months or OHS 0–1 at 6 months | sICH | Mortality at 3 months |
| Khatri et al 21 | USA | 58 | ≤5 | <3 | 66.2 (12.0) | 42 (72.4) | ICH with NIHSS ≥1 | 4 (4) | 46 (79.3) | 1 (1.7) | 1 (1.7) |
| Huisa et al 18 | USA | 133 | ≤5 | <3 | 68.5 (15.4) | 79 (59.4) | ICH with NIHSS ≥1 | 2.6 (1.5) | 85 (63.9) | 3 (2.3) | 6 (4.5) |
| Urra et al 12 | Spain | 203 | ≤5 | <4.5 | 68.9 (13.5) | 134 (66.0) | ICH with NIHSS ≥4 | 3 (2–4) 2 (1–3.8) | 167 (82.3) | 0 | 5 (2.5) |
| Greisenegger et al 11 | Austria | 890 | ≤5 | <3 | 70 (61–78) 70 (62–78) | 518 (58.2) | ICH with NIHSS ≥1 | 4 (3–5) | 609 (68.4) | 11 (1.2) | 27 (3.0) |
| Nesi et al 13 | Italy | 128 | ≤6 | <3 | 65.6 (11.6) | 92 (71.9) | ICH with NIHSS ≥1 | NA | 108 (84.4) | 0 | 0 |
| Khatri et al 14 | USA | 106 | ≤5 | <3 | 82 81 | 63 (59.4) | ICH with significant neurological deterioration | 4 | 59 (55.7) | 0 | 3 (2.8) |
| Ng et al 16 | Australia | 73 | ≤3 | <4.5 | 73.2 (67.3–82.8) | 45 (61.6) | ICH with NIHSS ≥4 | 2 (1–3) | 59 (80.8) | 0 | 0 |