Indications | Contraindications* | Absolute vs relative contraindication |
Large and/or deep aneurysms in narrow corridors where temporary clip ligation is difficult or not possible | Severe reactive airway disease | Absolute |
In synergy with temporary clipping, especially during intraoperative aneurysmal rupture | Severe coronary artery disease | Absolute |
Instances in which temporary clipping fails | Pre-existing cardiac conduction abnormalities | Relative |
To improve visualisation of adjacent perforating arteries | Allergy | Relative |
Dipyridamole, methylxanthines and nimodipine inhibit adenosine breakdown and uptake and can increase levels | Relative | |
Calcified or fibrotic aneurysmal wall/dome | Relative |
*Mostly provided as expert opinion by Khan et al.15